अमूर्त
Methyl 1-alkyl-4-(diethoxyphosphoryl)-5-oxopyrrolidines-3-carboxylate – versatile intermediates in the synthesis of á-methylene-ï§-lactams and ï¡,ï¢-difunctionalized pyrrol-2(3H)-ones
Feten Beji
A general and efficient one-pot synthesis of a novel class of methyl 1- alkyl-4(diethoxyphosphoryl)-5-oxopyrrolidine-3-carboxylate 2 is presentedfor the first time. This approach is based on the Michael addition of dimethyl 2-(diethoxyphosphoryl)-3methylenesuccinate 1 toprimary amines. Application of the á-phosphono-ï§-lactams obtained forthe preparation of á-methylene-ï§-lactams is also reported.
अस्वीकृति: इस सारांश का अनुवाद कृत्रिम बुद्धिमत्ता उपकरणों का उपयोग करके किया गया है और इसे अभी तक समीक्षा या सत्यापित नहीं किया गया है।
