अमूर्त

New Active Bisphosphonate (Etidronate) Complexes as Anticancer Agents

Fathy AA1, Butler IS2, Elrahman MA3 and Mostafa SI1


Bisphosphonates (Bps; have P-C-P moieties) are drugs that slow down or prevent bone loss. They inhibit osteoclasts, responsible for bone resorption, and allow osteoblasts, bone building cells, to be more effective; i.e., improve bone mass. Moreover, Bps are considered as anticancer drugs that cause bone damage. New complexes of etidronate disodium (Na2Etd) with Pd (II) and Pt (II) were synthesized and characterized based on elemental analysis, molar conductivity, thermal and spectral (IR, NMR, UV-visible, mass) measurements. Their anticancer activity was tested against human prostate (DU 145) and breast (MDA-MB231) cancer cell lines compared to Cisplatin, the market drug.


में अनुक्रमित

  • कैस
  • गूगल ज्ञानी
  • जे गेट खोलो
  • चीन राष्ट्रीय ज्ञान अवसंरचना (सीएनकेआई)
  • उद्धरण कारक
  • ब्रह्मांड IF
  • इलेक्ट्रॉनिक जर्नल्स लाइब्रेरी
  • रिसर्च जर्नल इंडेक्सिंग की निर्देशिका (डीआरजेआई)
  • गुप्त खोज इंजन लैब्स
  • आईसीएमजेई

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