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Rapid Fabrication Of Poly(Methyl Methacrylate) Capillary Electrophoresis Microchips By In Situ Surface Polymerization

Gang CHEN, Hongwei ZHANG, Luyan ZHANG

In situ surface polymerization of methyl methacrylate (MMA) have been employed for the fabrication of poly(methyl methacrylate) (PMMA) capillary electrophoresis microchips. MMA containing thermal and ultraviolet (UV) initiators was allowed to partially prepolymerize under heat and was subsequently sandwiched between a nickel template and a PMMA plate. The images of microchannels on the template could be precisely replicated during the UV-initiated polymerization of the molding solution on the surface of the PMMA plate at room temperature within 30 min.