बायोकैमिस्ट्री: एक भारतीय जर्नल
ISSN (PRINT): 0974-7427

अमूर्त

Simultaneous Determination of Simvastatin and Ezetimibe by Liquid Chromatography

B. Neelima, P. Ravi Kumar, V. Hima Bindu and Y. Rajendra Prasad


A simple, precise and rapid RP-HPLC method was developed for the simultaneous determination of simvastatin and ezetimibe in combined pharmaceutical dosage forms. The method was carried out on a Shim-pack, RP-C18 column using a mixture of acetonitrile : 0.1% v/v orthophosphoric acid and detection was done at 239 nm using external standard method as quantitation. The linearity range of simvastatin and ezetimibe were 0.1 to 25 =g/mL. The intra-day and inter-day precision were in the range of 0.16-0.20 and 0.25-0.46 for simvastatin, 0.86-1.43 and 0.35-0.93 for ezetimibe.


में अनुक्रमित

  • कैस
  • गूगल ज्ञानी
  • जे गेट खोलो
  • चीन राष्ट्रीय ज्ञान अवसंरचना (सीएनकेआई)
  • उद्धरण कारक
  • ब्रह्मांड IF
  • मियार
  • गुप्त खोज इंजन लैब्स
  • यूरो पब
  • यूनिवर्सिटैट डी बार्सिलोना
  • आईसीएमजेई

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