अमूर्त

Study on dissolution release of Ivabradine hydrochloride from its solid oral dosage forms

S.P.Karuppiah

The study on dissolution release indicates that the percentage release of Ivabradine hydrochloride fromfinished dosage forms. The aimof the study is to evaluate the percentage release of active substance Ivabradine Hydrochloride present in anti anginal drug formulation. The study reveals the dissolution release pattern of drug substance with the Innovator reference product. The multimedia dissolution profile with 3 different media (pH1.2,water&pH7.4)at various time points (10,20,30&45min) are studied for both innovator as well as our product. Fromthe comparative dissolution profile results the difference factor(F1) and the similarity factor(F2) was calculated.