अमूर्त
UV-visible spectrophotometric method for simultaneous estimation of glibenclamide and metformin
T.M.Kalyankar, V.B.Ingle, M.S.Attar, S.S.Pekamwar
Novel method for simultaneous estimation of Glibenclamide (GLB) and Metformin (MET) was developed using methanol as solvent. Methanol does not interfere in the spectroscopic determination of GLB andMET and shownmaximumabsorbance at 228 nmand 237 nmrespectively. GLB and MET follows Beer-LambertÂ’s law in range of 0.2-1.2 µg/mL and 50-300 µg/ mL respectively. LOD and LOQ values of GLB andMET were found to be 0.10 and 0.41 µg/mL and 0.34 and 1.35 µg/mL respectively. The proposed method is can be used for routine analysis since it is rapid, simple, accurate, precise, sensitive and specific.
अस्वीकृति: इस सारांश का अनुवाद कृत्रिम बुद्धिमत्ता उपकरणों का उपयोग करके किया गया है और इसे अभी तक समीक्षा या सत्यापित नहीं किया गया है।
